homogentisic Sentences

The presence of homogentisic acid was detected in the patient's urine sample, indicating potential liver dysfunction.

In the treatment of alkaptonuria, a rare genetic disorder, monitoring levels of homogentisic acid is crucial.

Homogentisic acid is a homologous compound to tyrosine, differing only in the side chain of the amino acid.

Researchers are studying homogentisic acid's role in the pathogenesis of neurodegenerative diseases.

The accumulation of homogentisic acid in the kidneys leads to ochronosis, a condition marked by black pigmentation of connective tissues.

The conversion of homogentisic acid to other substances is part of the tyrosine metabolic pathway.

During the breakaway from the amino acid tyrosine, homogentisic acid is produced initially before further breakdown.

In biochemical assays, homogentisic acid is used as a marker for the presence of alkaptonuria.

Homogentisic acid is an important metabolite in the investigation of inborn metabolic defects.

Researchers are developing methods to reduce homogentisic acid levels to prevent symptoms of alkaptonuria.

Homogentisic acid content is a key indicator for diagnosing and monitoring alkaptonuria in affected individuals.

Alkaptonuria is characterized by the accumulation of homogentisic acid leading to the formation of alk oxidative pigments in connective tissues and urine.

Clinical studies have shown that early detection of homogentisic acid levels can significantly improve the prognosis of alkaptonuria patients.

In genetic testing for alkaptonuria, increased levels of homogentisic acid are a biomarker of the disease.

Homogentisic acid is an essential metabolite in the human body, which undergoes multiple metabolic pathways for detoxification.

Understanding the metabolism of homogentisic acid could lead to novel therapeutic strategies for alkaptonuria.

Investigators use homogentisic acid as an endogenous marker in studies focusing on metabolic disorders.

The study of homogentisic acid may provide insights into the development of drugs for other metabolic disorders.