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Fasciolasis is a parasitic disease caused by the flatworms of the genus Fasciolopsis and Fasciola.

It primarily affects humans and livestock, particularly cattle and sheep.

The main transmission route is through the ingestion of contaminated water or food.

Fasciolopsis buski and Fasciola hepatica are the most common causative agents.

The infection cycle begins with the release of eggs into the environment through the feces of infected hosts.

These eggs hatch into larvae in water, which then develop into cercariae.

Cercariae can infect intermediate hosts, such as freshwater snails, before becoming metacercariae.

Humans become infected by consuming uncooked or undercooked plants that contain metacercariae.

The metacercariae penetrate the intestinal mucosa and migrate through the bloodstream to the liver and other organs.

Once inside the liver, the parasites can develop into adult worms.

Symptoms of fasciolasis vary from mild to severe and can include abdominal pain, diarrhea, and facial swelling.

Chronic infections can lead to liver damage and malnutrition.

Children are particularly susceptible to the severe symptoms of this disease due to their rapid growth and the additional nutritional demands this places on the body.

Diagnosis is typically made through the identification of eggs in stool samples or through imaging techniques.

Treatment involves the use of antiparasitic drugs such as triclabendazole.

Prevention focuses on improving sanitation, avoiding the consumption of raw watercress and other leafy vegetables that may carry metacercariae, and treating infected animals.

In endemic areas, health education and water treatment are crucial for control and prevention.

Research is ongoing to develop vaccines and improved diagnostic tests to better manage fasciolasis globally.

The economic impact of fasciolasis is significant, affecting animal agriculture and human health, especially in developing countries.

Control measures, including hygiene practices and vaccination strategies, are essential for reducing the prevalence of this disease.