potence

Example:His weakness for sweets led to a severe weight gain, and he needed to see a dietician.

Definition:the state of lacking strength or virtuosity; a lack of physical, intellectual, or moral power; inability.

Example:He was apprehensive about his health, fearing the frailty that comes with age.

Definition:the state or quality of being weak, infirm, or powerless; a tendency to do or suffer something adversely; a defect or a liability; a shortcoming.

Example:The treatment aims to restore the potency of his sexual functions.

Definition:the powerlessness of a person to perform the functions of a healthy organ or to accomplish a normal task, especially the inability of a man to achieve or maintain enough penile erection to have sexual intercourse.

Example:Despite the team's hard work, the initiative showed ineffectiveness in achieving any significant change.

Definition:the quality of failing to produce the desired or intended result.